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[Prospec] CD207 Human

등록일2024. 11. 07
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[Prospec] CD207 Human

[Prospec] Product


어스바이오는 Prospec 한국 공식 대리점으로서 모든 제품을 전문적으로 취급 및 공급하고 있습니다.
Prospec의 CD Antigens 제품을 소개드립니다.
 

[Prospec] CD207 Human


CD207 Human
 

Product Information:

 

Catalogue number:

PRO-2204


Introduction:

CD207 (C-type lectin domain family 4 member K) is expressed in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. Moreover, CD207 is expressed in several other dendritic cell types including dermal CD103+ DCs and splenic CD8+ DCs. Langerin is localized in the Birbeck granules, the organelles present in the cytoplasm of Langerhans cells and comprised of superimposed and zippered membranes.

CD207 is a C-type lectin with mannose binding specificity, and it has been suggested that mannose binding by the CD207 protein leads to internalization of antigen into Birbeck granules thus providing access to a nonclassical antigen-processing pathway.



Description:

  • CD207 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 287 amino acids (65-328 a.a) and having a molecular mass of 32.2kDa.
  • CD207 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.


Source:

Escherichia Coli.


Physical Appearance:

Sterile Filtered clear solution.


Formulation:

CD207 protein solution (1mg/ml) containing 20mM Tris 8.0 and 10% glycerol.


Stability:

  • Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
  • For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
  • Avoid multiple freeze-thaw cycles.


Purity:

Greater than 85.0% as determined by SDS-PAGE.

 



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Tel : 02-862-2816 / email : bio@usbio.co.kr
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